How to Build a Single-Cell RNA-seq Analysis Pipeline with Scanpy for PBMC Clustering, Annotation, and Trajectory Discovery
In this tutorial, we perform an advanced single-cell RNA-seq analysis workflow using Scanpy on the PBMC-3k benchmark dataset. We start by loading the dataset, inspecting its structure, and applying quality control checks to evaluate gene counts, total counts, mitochondrial content, and ribosomal gen...
Cloudflare says AI made 1,100 jobs obsolete, even as revenue hit a record high
CloudFlare announced its first large-scale layoff. CEO Matthew Prince says because of AI efficiency gains, the company doesn't need as many support roles.
The “people’s airline” and the enterprise AI gold rush
Everyone wants a piece of the enterprise AI pie, and this week, we saw a string of companies making their moves. From Anthropic and OpenAI announcing new joint ventures targeting enterprise AI deployment to SAP dropping $1B on German AI startup Prior Labs, it’s becoming clear that if you’re a startu...
Last 24 hours to get 50% off a second pass to TechCrunch Disrupt 2026
Last day to buy one pass and get a second one at 50% off to TechCrunch Disrupt 2026. Bring a partner, co-founder, or colleague at half off. Register now.
The back office problem that explains why specialists never call you back
Like many AI companies automating work that humans currently do, Basata will eventually face a harder question about where the line is between augmenting workers and displacing them. For now, the founders say the administrative staff they work with aren't worried about that; they're more worried abo...
Regulating the Unregulatable: Why AI Governance Is Already Behind
AI governance is already lagging behind frontier model evolution. Explore why regulation built for static systems cannot keep pace with dynamic, rapidly advancing AI.
Exhibit at TechCrunch Disrupt 2026: Get in front of 10,000 decision-makers before space runs out
If startup visibility, traction, and real deals matter, you should be on the TechCrunch Disrupt 2026 exhibit floor. Get your 6' exhibit table before your competitor does.
Aurora’s Chris Urmson on why self-driving trucks are finally ready to scale
Self-driving has been “almost here” for over a decade. But somewhere between DARPA challenges and a handful of driverless trucks hauling freight between Dallas and Houston, Aurora co-founder and CEO Chris Urmson’s story changed. The self-driving truck company started commercial driverless operations...
2 days left: Get 50% off a second pass to TechCrunch Disrupt 2026
Two days left to save up to $410 on your pass, and get a second one at 50% off to TechCrunch Disrupt 2026. Offer ends May 8, 11:59 p.m. PT. Register now.
The Best Risk Mitigation Strategy in Data? A Single Source of Truth
Every data leader has a version of this story. A regulatory audit surfaces a metric that doesn’t match across systems. A board member catches conflicting revenue numbers in two reports presented back-to-back. An AI tool generates a recommendation based on data that hasn’t been governed since the ana...
OpenAI Introduces MRC (Multipath Reliable Connection): A New Open Networking Protocol for Large-Scale AI Supercomputer Training Clusters
MRC (Multipath Reliable Connection) is a new open networking protocol developed by OpenAI in partnership with AMD, Broadcom, Intel, Microsoft, and NVIDIA that improves GPU networking performance and resilience in large-scale AI training clusters by spreading packets across hundreds of paths simultan...
Five architects of the AI economy explain where the wheels are coming off
Earlier this week, five people who touch every layer of the AI supply chain sat down at the Milken Global Conference in Beverly Hills, where they talked with TechCrunch about everything from chip shortages to orbital data centers to the possibility that the whole architecture that undergirds the tec...
#496 – FFmpeg: The Incredible Technology Behind Video on the Internet
Jean-Baptiste Kempf is lead developer of VLC and president of VideoLAN. Kieran Kunhya is a longtime FFmpeg contributor, codec engineer, and the person behind the now-infamous FFmpeg account on X. Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep496-sc See below for...