Welcome to M5BMachine 5-Minute Briefing

GPT-5 Pro helped solve a 3-year-old immunology mystery, offering insights into T cell behavior. The breakthrough could support cancer and autoimmune research.

Learn how Jason Liu uses Codex to preserve context, manage complex projects, and help work continue beyond a single prompt.

Samsung Electronics deploys ChatGPT Enterprise and Codex to employees worldwide, marking one of OpenAI’s largest enterprise AI rollouts.

OpenAI introduces new spend controls and usage analytics for ChatGPT Enterprise, helping organizations manage costs and scale AI with confidence.

Learn how GPT-5.5 Instant improves ChatGPT’s health and wellness responses with stronger reasoning, better context, clearer communication, and physician-informed evaluations.

OpenAI and Molecule.one show how a near-autonomous AI chemist using GPT-5.4 improved a key drug-making reaction, advancing medicinal chemistry research.

Introducing LifeSciBench, an expert-authored, expert-reviewed benchmark for evaluating how AI systems handle real-world life science research tasks and decisions.

OpenAI launches the Partner Network, investing $150M to help global partners accelerate enterprise AI adoption, deployment, and transformation.

Preply uses OpenAI to launch AI-generated lesson summaries, providing personalised feedback and language learning exercises.

Learn how BBVA scaled ChatGPT Enterprise to 100,000 employees and partnered with OpenAI to accelerate AI-powered banking transformation worldwide.

A new report from OpenAI details PRC-linked influence operations using AI to target U.S. tech debates, data center narratives, tariffs, and false claims about ChatGPT.

See how LSEG uses OpenAI to scale trusted AI across its global business, accelerating insights, shrinking release cycles, and empowering 4,000 employees.

OpenAI recently submitted a confidential S-1 to the SEC and has not decided on timing.

OpenAI launches the Economic Research Exchange to study AI’s impact on jobs, productivity, and the economy. Applications are now open for selected research projects.

ChatGPT introduces a new memory system to better remember preferences, keeping context fresh and relevant across conversations.

An action plan for AI-powered biological resilience

GPT-Rosalind advances life sciences research with enhanced biological reasoning, medicinal chemistry expertise, genomics analysis, and experimental workflow capabilities.

OpenAI outlines its public policy agenda for AI, including safety, youth protection, workforce transition, and global standards to ensure AI benefits society.

OpenAI calls for global action on youth AI safety through a dedicated AI Safety Institute

Our approach to AI policy and political advocacy, transparency, support for thoughtful regulation and AI safety, and that no outside political group speaks on the company’s behalf.

How Braintrust engineers use Codex with GPT-5.5 to run experiments and code faster.

Boston Children’s Hospital uses OpenAI technology to improve patient care, reduce operational burden, and help diagnose more than 40 rare disease cases.

OpenAI launches Rosalind Biodefense, expanding trusted access to GPT-Rosalind for vetted developers and U.S. government partners advancing biodefense, public health, and pandemic preparedness through frontier AI.

Ahead of global elections, we’re helping people access information, supporting cyber defenders, and increasing AI transparency