Welcome to M5BMachine 5-Minute Briefing

OpenAI recently submitted a confidential S-1 to the SEC and has not decided on timing.

OpenAI launches the Economic Research Exchange to study AI’s impact on jobs, productivity, and the economy. Applications are now open for selected research projects.

ChatGPT introduces a new memory system to better remember preferences, keeping context fresh and relevant across conversations.

An action plan for AI-powered biological resilience

GPT-Rosalind advances life sciences research with enhanced biological reasoning, medicinal chemistry expertise, genomics analysis, and experimental workflow capabilities.

OpenAI outlines its public policy agenda for AI, including safety, youth protection, workforce transition, and global standards to ensure AI benefits society.

OpenAI calls for global action on youth AI safety through a dedicated AI Safety Institute

Our approach to AI policy and political advocacy, transparency, support for thoughtful regulation and AI safety, and that no outside political group speaks on the company’s behalf.

How Braintrust engineers use Codex with GPT-5.5 to run experiments and code faster.

Boston Children’s Hospital uses OpenAI technology to improve patient care, reduce operational burden, and help diagnose more than 40 rare disease cases.

OpenAI launches Rosalind Biodefense, expanding trusted access to GPT-Rosalind for vetted developers and U.S. government partners advancing biodefense, public health, and pandemic preparedness through frontier AI.

Ahead of global elections, we’re helping people access information, supporting cyber defenders, and increasing AI transparency

OpenAI partners with Grupo Folha and Grupo UOL to bring trusted Brazilian journalism to ChatGPT, expanding access to news with attribution and transparency.

How Virgin Atlantic used Codex to ship its revamped mobile app on a fixed holiday travel deadline, reaching near-total unit test coverage and zero P1 defects.

AdventHealth is using ChatGPT for Healthcare to streamline workflows, reduce administrative burden, and return more time to patient care.

How Ramp engineers use Codex with GPT-5.5 to review code and ship improvements, allowing them to get substantive feedback in minutes instead of hours.

See how sales teams can use Codex to create pipeline briefs, meeting prep packets, forecast reviews, account plans, and stalled-deal diagnoses from real work inputs.

See how business operations teams can use Codex to create initiative briefs, strategy updates, leadership decision packets, progress updates, and more from real work inputs.

Use Codex anywhere with the ChatGPT mobile app. Monitor, steer, and approve coding tasks in real time across devices and remote environments.

Learn how new ChatGPT safety updates improve context awareness in sensitive conversations, helping detect risk over time and respond more safely.

OpenAI details its response to the TanStack “Mini Shai-Hulud” supply chain attack, outlines protections taken to secure systems and signing certificates, and explains why macOS users must update OpenAI apps by June 12, 2026. Learn what happened, what was affected, and how OpenAI is strengthening def...

Learn how AutoScout24 Group uses Codex and ChatGPT to speed development cycles, improve code quality, and expand AI adoption.

ChatGPT adoption surged in Q1 2026, with fastest growth among users over 35 and more balanced gender usage, signaling broader mainstream AI adoption.

How enterprises scale AI: from early experiments to compounding impact through trust, governance, workflow design, and quality at scale.